Visual Psychophysics and Physiological Optics Cone Dystrophy With ‘‘Supernormal’’ Rod ERG: Psychophysical Testing Shows Comparable Rod and Cone Temporal Sensitivity Losses With No Gain in Rod Function

Citation: Stockman A, Henning GB, Michaelides M, et al. Cone dystrophy with ‘‘supernormal’’ rod ERG: psychophysical testing shows comparable rod and cone temporal sensitivity losses with no gain in rod function. Invest Ophthalmol Vis Sci. 2014;55:832–840. DOI:10.1167/iovs. 13-12919 PURPOSE. We report a psychophysical investigation of 5 observers with the retinal disorder ‘‘cone dystrophy with supernormal rod ERG,’’ caused by mutations in the gene KCNV2 that encodes a voltage-gated potassium channel found in rod and cone photoreceptors. We compared losses for rodand for cone-mediated vision to further investigate the disorder and to assess whether the supernormal ERG is associated with any visual benefit.